The PI3 Kinase p110 Beta Monoclonal Antibody (CAB1271) is a specialized research tool designed for studying the PI3 Kinase p110 Beta protein, a key player in the PI3 kinase signaling pathway. This monoclonal antibody, developed for use in various research applications, specifically recognizes the p110 Beta isoform of PI3 Kinase and is highly reactive with human samples.The PI3 Kinase p110 Beta antibody facilitates the detection and analysis of the p110 Beta protein in a variety of cell types, making it an essential tool for research in molecular biology, cell signaling, and cancer biology. By targeting this specific isoform of PI3 Kinase, researchers can gain insights into the role of the PI3 kinase signaling pathway in various cellular processes, including cell growth, proliferation, and survival.
With its validated performance in Western blot applications, the PI3 Kinase p110 Beta Monoclonal Antibody (CAB1271) is a reliable and accurate tool for studying the function and regulation of PI3 Kinase p110 Beta in both normal and disease states. Its utility in immunology and cancer research makes it a valuable asset for scientists striving to understand the complexities of signaling pathways and develop targeted therapies for a wide range of diseases.
Product Name:
PI3 Kinase p110 beta Monoclonal Antibody
SKU:
CAB1271
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PI3 Kinase p110 beta (NP_006210.1).
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5291
Clone Number:
ARC0703
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PI3 Kinase p110 beta Rabbit mAb (CAB1271) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
