The PI 3-Kinase p55-gamma Rabbit Monoclonal Antibody (CAB3980) is a highly specific antibody designed for research involving the PI 3-Kinase p55-gamma protein. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications including Western blot and immunohistochemistry.PI 3-Kinase p55-gamma is a key enzyme involved in cellular signaling pathways, particularly in the regulation of cell growth, proliferation, and survival. Dysregulation of PI 3-Kinase signaling has been implicated in various diseases, including cancer, diabetes, and cardiovascular disorders.
Understanding the function and regulation of PI 3-Kinase p55-gamma is crucial for developing targeted therapies for these diseases.This antibody binds specifically to the PI 3-Kinase p55-gamma protein, enabling accurate detection and analysis in different cell types and tissues. Its high specificity and sensitivity make it an essential tool for researchers in the fields of cell biology, cancer biology, and drug discovery. Invest in the PI 3-Kinase p55-gamma Rabbit Monoclonal Antibody (CAB3980) for reliable and reproducible results in your research experiments.
Product Name:
PIK3R3/p55PIK Rabbit Monoclonal Antibody
SKU:
CAB3980
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 362-461 of human PIK3R3/p55PIK (Q92569).
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity.
Purification Method:
Affinity purification
Gene ID:
8503
Clone Number:
ARC0320
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PIK3R3/p55PIK Rabbit mAb (CAB3980) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
