The PI 3 Kinase Class 3 Rabbit Monoclonal Antibody is a valuable tool for researchers studying the PI 3 Kinase Class 3 protein, a crucial regulator of cell growth, proliferation, and survival. This antibody, generated in rabbits, is highly specific for human samples and is optimized for use in Western blot applications. It binds specifically to the PI 3 Kinase Class 3 protein, allowing for precise detection and analysis in a variety of cell types.The PI 3 Kinase Class 3 protein, also known as Vps34, plays a vital role in autophagy, a cellular process that degrades and recycles damaged organelles and proteins. Dysregulation of autophagy has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
By targeting the PI 3 Kinase Class 3 protein, researchers can gain insights into the mechanisms underlying these diseases and develop potential therapeutic interventions.Overall, the PI 3 Kinase Class 3 Rabbit Monoclonal Antibody is a valuable asset for scientists conducting research in the fields of cell biology, cancer biology, and neurology. Its high specificity and sensitivity make it an essential tool for studying the complex functions of the PI 3 Kinase Class 3 protein in health and disease.
Product Name:
PIK3C3/VPS34 Rabbit Monoclonal Antibody
SKU:
CAB12295
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 788-887 of human PIK3C3/VPS34 (Q8NEB9).
WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells
Synonyms:
VPS34; Vps34; hVps34; PIK3C3/VPS34
Positive Sample:
RD,Mouse brain,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasmic vesicle, Late endosome, Midbody, autophagosome.
Calculated MW:
102kDa
Observed MW:
100kDa
Enables 1-phosphatidylinositol-3-kinase activity. Involved in early endosome to late endosome transport and regulation of cytokinesis. Acts upstream of or within autophagy and protein lipidation. Located in autolysosome; late endosome; and midbody.
Purification Method:
Affinity purification
Gene ID:
5289
Clone Number:
ARC0286
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIK3C3/VPS34 Rabbit mAb (CAB12295) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
