PHYKPL Antibody (PACO15355)
- SKU:
- PACO15355
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PHYKPL Antibody (PACO15355)
The PHYKPL Polyclonal Antibody (PACO15355) is a valuable tool for research involving PHYKPL, a key enzyme involved in the metabolism of phytol, a precursor for vitamin E biosynthesis. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting.PHYKPL plays a crucial role in lipid metabolism and has been linked to various diseases, including metabolic disorders and neurodegenerative conditions.
By detecting and analyzing PHYKPL protein levels, researchers can gain valuable insights into the role of this enzyme in health and disease.The PHYKPL Polyclonal Antibody is an essential tool for studies in biochemistry, nutrition, and pharmaceutical research, providing researchers with the means to explore the functions and potential therapeutic targets associated with PHYKPL.
| Antibody Name: | PHYKPL Antibody (PACO15355) |
| Antibody SKU: | PACO15355 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human AGXT2L2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human lymphoma tissue, Primary antibody: PACO15355(AGXT2L2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
| Background: | This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. |
| Synonyms: | 5-phosphohydroxy-L-lysine phospho-lyase |
| UniProt Protein Function: | AGXT2L2: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 4.2.3.134; TransferaseChromosomal Location of Human Ortholog: 5q35.3Cellular Component: mitochondrial matrixMolecular Function: identical protein binding; lyase activity; protein binding; pyridoxal phosphate binding; transaminase activityBiological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; lysine catabolic processDisease: Phosphohydroxylysinuria |
| UniProt Protein Details: | |
| NCBI Summary: | This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
| UniProt Code: | Q8IUZ5 |
| NCBI GenInfo Identifier: | 74750645 |
| NCBI Gene ID: | 85007 |
| NCBI Accession: | Q8IUZ5.1 |
| UniProt Secondary Accession: | Q8IUZ5,Q8WYS6, Q96HW8, A8K7P6, B3KN36, D3DWP9 |
| UniProt Related Accession: | Q8IUZ5 |
| Molecular Weight: | 18,857 Da |
| NCBI Full Name: | 5-phosphohydroxy-L-lysine phospho-lyase |
| NCBI Synonym Full Names: | 5-phosphohydroxy-L-lysine phospho-lyase |
| NCBI Official Symbol: | PHYKPLÂ Â |
| NCBI Official Synonym Symbols: | PHLU; AGXT2L2Â Â |
| NCBI Protein Information: | 5-phosphohydroxy-L-lysine phospho-lyase |
| UniProt Protein Name: | 5-phosphohydroxy-L-lysine phospho-lyase |
| UniProt Synonym Protein Names: | Alanine--glyoxylate aminotransferase 2-like 2 |
| Protein Family: | |
| UniProt Gene Name: | PHYKPLÂ Â |
| UniProt Entry Name: | AT2L2_HUMAN |
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