The PHYKPL Polyclonal Antibody (PACO07651) is a valuable tool for researchers studying the PHYKPL protein, which is involved in the phosphorylation of phosphatidyl inositol. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.PHYKPL is an important enzyme in lipid metabolism and is implicated in various physiological processes, including cell signaling and membrane trafficking. Research on PHYKPL is essential for understanding its role in lipid homeostasis and its potential implications in metabolic disorders such as diabetes and obesity.
By using the PHYKPL Polyclonal Antibody in their studies, researchers can accurately detect and analyze PHYKPL protein levels in different cell types, allowing for a deeper understanding of its functions and mechanisms of action. This antibody is a valuable tool for investigations into lipid biology, metabolic diseases, and potential therapeutic targets in related conditions.
AGXT2L2: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 4.2.3.134; TransferaseChromosomal Location of Human Ortholog: 5q35.3Cellular Component: mitochondrial matrixMolecular Function: identical protein binding; lyase activity; protein binding; pyridoxal phosphate binding; transaminase activityBiological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; lysine catabolic processDisease: Phosphohydroxylysinuria
UniProt Protein Details:
NCBI Summary:
This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
