The PHPT1 Polyclonal Antibody (CAB1127) is a powerful tool for researchers studying PHPT1, a key enzyme involved in protein L-histidine phosphorylation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is optimized for use in Western blot applications. By binding specifically to the PHPT1 protein, researchers can detect and analyze PHPT1 expression in a variety of cell types, making it an essential tool for studies in biochemistry and cell signaling pathways.PHPT1 is known for its role in regulating cellular processes through the phosphorylation of histidine residues on target proteins.
This enzyme plays a crucial function in modulating protein activity and function, making it a promising target for research aimed at understanding cellular signaling mechanisms and protein modifications. Insights gained from studying PHPT1 may have implications for drug discovery and therapeutic interventions targeting diseases such as cancer and metabolic disorders. Overall, the PHPT1 Polyclonal Antibody (CAB1127) provides researchers with a reliable means to investigate the role of PHPT1 in cellular signaling pathways, offering potential insights into novel therapeutic approaches for a range of human health conditions.
Product Name:
PHPT1 Rabbit Polyclonal Antibody
SKU:
CAB1127
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human PHPT1 (NP_054891.2).
This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29085
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PHPT1 Rabbit pAb (CAB1127) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
