The Phospholipase D2 Polyclonal Antibody (CAB10192) is a valuable tool for researchers studying the role of Phospholipase D2 in cellular function. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the Phospholipase D2 protein, this antibody allows for accurate detection and analysis in a variety of cell types.Phospholipase D2 is an enzyme involved in lipid signaling pathways that regulate processes such as cell proliferation, migration, and intracellular vesicle trafficking.
Dysregulation of Phospholipase D2 has been implicated in various diseases, including cancer, neurological disorders, and inflammatory conditions. As such, understanding the function of Phospholipase D2 is crucial for developing targeted therapies and treatment strategies.Researchers in the fields of cell biology, biochemistry, and pharmacology can benefit from using the Phospholipase D2 Polyclonal Antibody in their studies. Its high specificity and reliability make it an essential tool for investigating the role of Phospholipase D2 in health and disease.
Product Name:
PLD2 Rabbit Polyclonal Antibody
SKU:
CAB10192
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PLD2 (NP_002654.3).
The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5338
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PLD2 antibody (CAB10192) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
