PLA2G1B Rabbit Polyclonal Antibody (CAB5478)
- SKU:
- CAB5478
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PLA2G1B Rabbit Polyclonal Antibody |
SKU: | CAB5478 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-148 of human PLA2G1B (NP_000919.1). |
Sequence: | AVWQ FRKM IKCV IPGS DPFL EYNN YGCY CGLG GSGT PVDE LDKC CQTH DNCY DQAK KLDS CKFL LDNP YTHT YSYS CSGS AITC SSKN KECE AFIC NCDR NAAI CFSK APYN KAHK NLDT KKYC QS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 |
Synonyms: | PLA2; PLA2A; PPLA2; PLA2G1B |
Positive Sample: | A-549,Mouse pancreas,Mouse small intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 16kDa |
Observed MW: | 16kDa |
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.
Purification Method: | Affinity purification |
Gene ID: | 5319 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |