The Phospho-YWHAZ (S58) Polyclonal Antibody (CABP0195) is a valuable tool for researchers studying the phosphorylation of YWHAZ, a protein involved in cell signaling pathways and regulation of cellular processes. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It targets the phosphorylated form of YWHAZ at serine 58, allowing for precise detection and analysis in various cell types.Phosphorylation of YWHAZ at serine 58 is known to regulate its binding to target proteins and influence downstream signaling cascades.
Research has shown that dysregulation of this phosphorylation event can impact cell proliferation, survival, and migration, making it a key focus in cancer biology and other disease-related studies. By utilizing the Phospho-YWHAZ (S58) Polyclonal Antibody, researchers can gain insights into the functional significance of YWHAZ phosphorylation and its potential as a therapeutic target for various diseases.
Product Name:
Phospho-YWHAZ-S58 Rabbit Polyclonal Antibody
SKU:
CABP0195
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A phospho specific peptide corresponding to residues surrounding S58 of human YWHAZ
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
7534
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using Phospho-YWHAZ-S58 Rabbit pAb (CABP0195).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
