Anti-Phospho-YAP1-S127 Antibody (CABP0489)
- SKU:
- CABP0489
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Antibody Name: | Anti-Phospho-YAP1-S127 Antibody |
Antibody SKU: | CABP0489 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1). |
Application: | WB IHC IF |
Recommended Dilution: | WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | NIH/3T3 |
Immunogen: | A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | AHSS P |
Gene ID: | 10413 |
Uniprot: | P46937 |
Cellular Location: | Cytoplasm, Nucleus |
Calculated MW: | 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa |
Observed MW: | 68kDa |
Synonyms: | COB1, YAP, YAP2, YAP65, YKI, YAP1 |
Background: | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Code: | P46937 |
NCBI GenInfo Identifier: | 294862479 |
NCBI Gene ID: | 10413 |
NCBI Accession: | P46937.2 |
UniProt Secondary Accession: | P46937,Q7Z574, B4DTY1, B7ZA01, E3WEB5, E3WEB6, E9PRV2 F5H202, K0KQ18, K0KYZ8, K0L195, K0L1G3, |
UniProt Related Accession: | P46937 |
Molecular Weight: | 504 |
NCBI Full Name: | Transcriptional coactivator YAP1 |
NCBI Synonym Full Names: | Yes-associated protein 1 |
NCBI Official Symbol: | YAP1Â Â |
NCBI Official Synonym Symbols: | YAP; YKI; COB1; YAP2; YAP65Â Â |
NCBI Protein Information: | transcriptional coactivator YAP1; yorkie homolog; protein yorkie homolog; yes-associated protein 2; 65 kDa Yes-associated protein; yes-associated protein YAP65 homolog |
UniProt Protein Name: | Transcriptional coactivator YAP1 |
UniProt Synonym Protein Names: | Protein yorkie homolog; Yes-associated protein YAP65 homolog |
Protein Family: | Transcriptional coactivator |
UniProt Gene Name: | YAP1Â Â |
UniProt Entry Name: | YAP1_HUMAN |