Vinculin Rabbit Polyclonal Antibody (CAB14193)
- SKU:
- CAB14193
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Vinculin Rabbit Polyclonal Antibody |
SKU: | CAB14193 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 751-850 of human Vinculin (NP_054706.1). |
Sequence: | AGAT SIAR RANR ILLV AKRE VENS EDPK FREA VKAA SDEL SKTI SPMV MDAK AVAG NISD PGLQ KSFL DSGY RILG AVAK VREA FQPQ EPDF PPPP PDLE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | MV; MVCL; CMD1W; CMH15; HEL114; Vinculin |
Positive Sample: | HeLa,PC-12,RD,Mouse lung,Rat lung,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, adherens junction, cytoskeleton, focal adhesion. |
Calculated MW: | 124kDa |
Observed MW: | 124kDa |
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 7414 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |