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Phospho-TP73-Y99 Rabbit Polyclonal Antibody (CABP0465)

SKU:
CABP0465
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
$503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-TP73-Y99 Rabbit Polyclonal Antibody
SKU:CABP0465
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:A phospho specific peptide corresponding to residues surrounding Y99 of human TP73
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:P73; CILD47; Phospho-TP73-Y99
Positive Sample:MCF7
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:70kDa
Observed MW:80kDa

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

Purification Method:Affinity purification
Gene ID:7161
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of MCF7, using Phospho-TP73-Y99 Rabbit pAb (CABP0465) at 1:500 dilution.MCF7 cells were treated by pervanadate (1 mM) at 37℃ for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.

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