The TNS1 Polyclonal Antibody (CAB17544) is a powerful tool for researchers studying TNS1, a protein involved in cellular adhesion and migration processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity when used with human samples, making it an ideal choice for Western blot applications. By specifically binding to the TNS1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, facilitating investigations in areas such as cell biology, cancer metastasis, and tissue development.TNS1, also known as Tensin-1, plays a crucial role in cell signaling pathways that regulate cell adhesion dynamics and migration behaviors. Its involvement in processes like cell spreading and tissue organization makes it a key player in physiological and pathological conditions.
Research on TNS1 can provide valuable insights into mechanisms underlying cancer progression, wound healing, and tissue remodeling, offering potential therapeutic targets for various diseases.In conclusion, the TNS1 Polyclonal Antibody is a valuable tool for researchers interested in unraveling the functions of TNS1 in cellular processes. Its reliability and precision make it a key asset in advancing scientific knowledge and discovering new therapeutic opportunities in the fields of cancer biology, regenerative medicine, and tissue engineering.
Product Name:
TNS1 Rabbit Polyclonal Antibody
SKU:
CAB17544
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TNS1 (NP_072174.3).
Sequence:
MSVS RTME DSCE LDLV YVTE RIIA VSFP STAN EENF RSNL REVA QMLK SKHG GNYL LFNL SERR PDIT KLHA KVLE FGWP DLHT PALE KICS ICKA MDTW LNAD PHNV VV
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
7145
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse heart, using TNS1 Rabbit pAb (CAB17544) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
