Phospho-TAK1-S439 Monoclonal Antibody (CAB9437)
- SKU:
- CAB9437
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | Phospho-TAK1-S439 Monoclonal Antibody |
SKU: | CAB9437 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic phosphorylated peptide around S439 of human TAK1 (O43318). |
Sequence: | RRSI Q |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CSCF; FMD2; TAK1; MEKK7; TGF1a; Phospho-TAK1-S439 |
Positive Sample: | C2C12+TGF-β |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm |
Calculated MW: | 67kDa |
Observed MW: | 75kDa |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 6885 |
Clone Number: | ARC2714 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |