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Phospho-Syk-Y525/526 Rabbit Polyclonal Antibody (CABP0542)

SKU:
CABP0542
Product Type:
Antibody
Applications:
WB
IP
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
€419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-Syk-Y525/526 Rabbit Polyclonal Antibody
SKU:CABP0542
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:A synthetic phosphorylated peptide around Y525 & Y526 of human Syk (NP_003168.2).
Sequence:ENYY KA
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:IMD82; p72-Syk; Phospho-Syk-Y525/526
Positive Sample:Jurkat
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Cytoplasm, cytosol.
Calculated MW:72kDa
Observed MW:72kDa

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:6850
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Jurkat cells, using Phospho-Syk-Y525/526 Rabbit pAb (CABP0542) at 1:1000 dilution. Jurkat cells were treated by 10% FBS for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.

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