The Phospho-Stathmin S25 Polyclonal Antibody (CABP0220) is a valuable tool for researchers studying the phosphorylation of Stathmin, a protein involved in microtubule dynamics and cell cycle progression. This antibody, generated in rabbits, specifically detects the phosphorylated form of Stathmin at serine 25 in human samples and is validated for use in Western blot applications. By targeting this specific phosphorylation site, researchers can gain insight into the regulation of Stathmin activity and its impact on cellular processes.Stathmin is known for its role in regulating microtubule dynamics, which are essential for various cellular functions such as cell division, cell shape maintenance, and intracellular transport. Phosphorylation of Stathmin at serine 25 has been linked to changes in microtubule organization and dynamics, impacting cell migration, cytoskeletal reorganization, and cell signaling pathways.
Understanding the phosphorylation status of Stathmin is crucial for deciphering its contribution to cell physiology and pathology.Researchers studying cell biology, cancer biology, and signaling pathways will benefit from the specific detection of phospho-Stathmin S25 provided by this antibody. By elucidating the role of Stathmin phosphorylation in disease states such as cancer, neurodegenerative disorders, and developmental abnormalities, this antibody enables deeper insights into the molecular mechanisms underlying these conditions. With its high reactivity and specificity, the Phospho-Stathmin S
Product Name:
Phospho-Stathmin 1-S25 Rabbit Polyclonal Antibody
SKU:
CABP0220
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic phosphorylated peptide around S25 of human Stathmin 1 (NP_005554.1).
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3925
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Phospho-Stathmin 1-S25 Rabbit pAb (CABP0220) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
