The Phospho-Stathmin-1 (S25) Monoclonal Antibody is a valuable tool for researchers studying the phosphorylation of Stathmin-1 at serine 25, a critical post-translational modification that regulates microtubule dynamics and cell division. This antibody, produced against the phosphorylated form of Stathmin-1, is highly specific and sensitive for detecting phosphorylated Stathmin-1 in human samples.Phosphorylation of Stathmin-1 at S25 is known to influence cell cycle progression, cell migration, and cytoskeleton organization, making it a key player in cancer progression and metastasis.
By targeting this specific phosphorylation site, researchers can gain insights into the role of Stathmin-1 in cancer biology and potentially identify novel therapeutic targets.Validated for use in Western blot applications, the Phospho-Stathmin-1 (S25) Monoclonal Antibody enables precise detection and quantification of phosphorylated Stathmin-1 in various cell types and experimental conditions. Its high specificity and sensitivity make it a reliable tool for studying the functional significance of phosphorylated Stathmin-1 in cancer and other disease contexts.
Product Name:
Phospho-Stathmin 1-S25 Monoclonal Antibody
SKU:
CABP1440
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic phosphorylated peptide around S25 of human Stathmin 1（NP_005554.1）.
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3925
Clone Number:
ARC62298
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of C6, using Phospho-Stathmin 1-S25 Rabbit mAb (CABP1440) at 1:1000 dilution.C6 cells were treated by PMA/TPA (200 nM) at 37℃ for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
