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Phospho-SRF-S103 Rabbit Polyclonal Antibody (CABP0829)

SKU:
CABP0829
Product Type:
Antibody
Applications:
WB
IHC
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-Phospho-SRF-S103 pAb Antibody CABP0829
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-Phospho-SRF-S103 pAb Antibody CABP0829
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-Phospho-SRF-S103 pAb Antibody CABP0829
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-Phospho-SRF-S103 pAb Antibody CABP0829
€419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-SRF-S103 Rabbit Polyclonal Antibody
SKU:CABP0829
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic phosphorylated peptide around S103 of human SRF (NP_003122.1).
Sequence:SLSE M
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:100
Synonyms:MCM1; Phospho-SRF-S103
Positive Sample:HeLa
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:52kDa
Observed MW:70kDa

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:6722
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from HeLa cells, using Phospho-SRF-S103 Rabbit pAb (CABP0829) at 1:1000 dilution. HeLa cells were treated by PMA/TPA (200nM) for 15 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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