Phospho-SRC Family-Y416 Monoclonal Antibody (CABP1370)
- SKU:
- CABP1370
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Phospho-SRC Family-Y416 Monoclonal Antibody |
SKU: | CABP1370 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around Y416 of human SRC Family (NP_005408.1). |
Sequence: | NEYT AR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ASV; SRC1; THC6; c-SRC; p60-Src; SRC; Phospho-SRC Family-Y416 |
Positive Sample: | HepG2+TGFβ,NIH/3T3,NIH/3T3+PDGF,C6+Pervanadate |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Mitochondrion inner membrane, Nucleus, Cytoskeleton. |
Calculated MW: | 60kDa |
Observed MW: | 62kDa/60kDa |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2534/3055/3932/4067/6714/7525 |
Clone Number: | ARC57736 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |