Phospho-SQSTM1/p62-S349 Polyclonal Antibody (CAB20737)
- SKU:
- CAB20737
- Product Type:
- Antibody
- Antibody Type:
- Secondary Antibody
- Host Species:
- Goat
- Isotype:
- Cy3 conjugated IgG
Frequently bought together:
Description
Product Name: | Phospho-SQSTM1/p62-S349 Polyclonal Antibody |
SKU: | CAB20737 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around S349 of human SQSTM1/p62 (NP_003891.1). |
Sequence: | DPST G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3; Phospho-SQSTM1/p62-S349 |
Positive Sample: | HeLa treated by MG132,C6 treated by MG132,NIH/3T3 treated by MG132 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Late endosome, Lysosome, Nucleus, P-body, autophagosome. |
Calculated MW: | 48kDa |
Observed MW: | 62kDa |
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Purification Method: | Affinity purification |
Gene ID: | 8878 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |