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Phospho-Smad3-T179 Rabbit Polyclonal Antibody (CABP0554)

SKU:
CABP0554
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
  • Immunology Antibodies 3 Anti-Phospho-SMAD3-T179 Antibody CABP0554
  • Immunology Antibodies 3 Anti-Phospho-SMAD3-T179 Antibody CABP0554
  • Immunology Antibodies 3 Anti-Phospho-SMAD3-T179 Antibody CABP0554
  • Immunology Antibodies 3 Anti-Phospho-SMAD3-T179 Antibody CABP0554
  • Immunology Antibodies 3 Anti-Phospho-SMAD3-T179 Antibody CABP0554
€419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-Smad3-T179 Rabbit Polyclonal Antibody
SKU:CABP0554
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic phosphorylated peptide around T179 of human Smad3 (NP_005893.1).
Sequence:PETP P
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:LDS3; mad3; LDS1C; MADH3; JV15-2; hMAD-3; hSMAD3; HSPC193; HsT17436; Phospho-Smad3-T179
Positive Sample:HeLa,PC-12
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:48kDa
Observed MW:48kDa

The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3.

Purification Method:Affinity purification
Gene ID:4088
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from HeLa cells, using Phospho-Smad3-T179 Rabbit pAb (CABP0554). The lane on the right is treated with the antigen-specific peptide.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.

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