Phospho-SIRT1-S47 Rabbit Monoclonal Antibody (CABP0976)
- SKU:
- CABP0976
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Phospho-SIRT1-S47 Rabbit Monoclonal Antibody |
SKU: | CABP0976 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around S47 of human SIRT1 (Q96EB6). |
Sequence: | ERSP G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | SIR2; SIR2L1; SIR2alpha; Phospho-SIRT1-S47 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Nucleus, Nucleus, PML body. |
Calculated MW: | 82kDa |
Observed MW: | 120kDa |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23411 |
Clone Number: | ARC1520 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |