The Phospho-SGK2 (T244) Polyclonal Antibody (PAC002543) is an essential tool for studying the phosphorylation of SGK2 at threonine 244, a key regulatory event in the activation of this serine/threonine protein kinase. This antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting the phosphorylated form of SGK2 in human samples, making it a valuable asset in phospho-protein research.SGK2, a member of the serum and glucocorticoid-regulated kinase (SGK) family, plays a crucial role in various cellular processes such as cell survival, proliferation, and ion transport. Phosphorylation at threonine 244 activates SGK2, leading to downstream signaling cascades that impact cell function and homeostasis.
Understanding the phosphorylation status of SGK2 is essential for deciphering its role in physiological and pathological conditions, making this antibody an invaluable resource for researchers in the fields of cell biology and signal transduction.With its ability to specifically recognize phospho-SGK2 at threonine 244, this antibody is suitable for a range of applications, including Western blotting and immunohistochemistry. Its reliability and accuracy make it a trusted tool for investigating the molecular mechanisms underlying SGK2 activation and its consequences in health and disease. Invest in the Phospho-SGK2 (T244) Polyclonal Antibody for groundbreaking discoveries
Antibody Name:
Phospho-SGK223 (Y413) Antibody
Antibody SKU:
PACO02543
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from human Pragmin around the phosphorylation site of Y413.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SGK223: a protein kinase of the NKF3 family. Protein type: EC 2.7.10.2; Kinase, protein; Motility/polarity/chemotaxis; NKF3 family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)Chromosomal Location of Human Ortholog: 8p23.1Molecular Function: protein kinase activity
UniProt Protein Details:
NCBI Summary:
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014]
