SGK1 Rabbit Polyclonal Antibody (CAB1025)
- SKU:
- CAB1025
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | SGK1 Rabbit Polyclonal Antibody |
SKU: | CAB1025 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 172-431 of human SGK1 (NP_005618.2). |
Sequence: | LYFV LDYI NGGE LFYH LQRE RCFL EPRA RFYA AEIA SALG YLHS LNIV YRDL KPEN ILLD SQGH IVLT DFGL CKEN IEHN STTS TFCG TPEY LAPE VLHK QPYD RTVD WWCL GAVL YEML YGLP PFYS RNTA EMYD NILN KPLQ LKPN ITNS ARHL LEGL LQKD RTKR LGAK DDFM EIKS HVFF SLIN WDDL INKK ITPP FNPN VSGP NDLR HFDP EFTE EPVP NSIG KSPD SVLV TASV KEAA EAFL GFSY APPT DSFL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SGK; SGK1 |
Positive Sample: | SK-MEL-28,Mouse brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Endoplasmic reticulum membrane, Mitochondrion, Nucleus. |
Calculated MW: | 49kDa |
Observed MW: | 45-60kDa |
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6446 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |