The RRN3 Polyclonal Antibody (CAB16705) is a valuable tool for researchers studying RRN3, a key regulator of RNA polymerase I transcription. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the RRN3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.
RRN3 is essential for the transcription of ribosomal RNA genes, playing a crucial role in ribosome biogenesis and cell growth. Dysregulation of RRN3 has been implicated in cancer progression, making it a promising target for therapeutic interventions. The RRN3 Polyclonal Antibody provides researchers with a powerful tool to investigate the molecular mechanisms underlying RRN3 function, offering insights that may drive the development of novel cancer treatments.
Product Name:
RRN3 Rabbit Polyclonal Antibody
SKU:
CAB16705
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 550-651 of human RRN3 (NP_060897.3).
Enables RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in transcription initiation from RNA polymerase I promoter. Predicted to act upstream of or within several processes, including DNA-templated transcription, initiation; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of transcription, DNA-templated. Located in nucleolus.
Purification Method:
Affinity purification
Gene ID:
54700
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RRN3 Rabbit pAb (CAB16705) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
