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Phospho-RELB-S573 Polyclonal Antibody (CABP1297)

SKU:
CABP1297
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €489
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-RELB-S573 Polyclonal Antibody
SKU:CABP1297
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse
Immunogen:A synthetic phosphorylated peptide around S573 of human RELB (NP_006500.2).
Sequence:LLSP G
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:IREL; I-REL; IMD53; REL-B; Phospho-RELB-S573
Positive Sample:A20
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center.
Calculated MW:62kDa
Observed MW:75kDa

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in cytosol and nucleoplasm. Part of chromatin; nucleus; and transcription repressor complex. Colocalizes with centrosome. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma.

Purification Method:Affinity purification
Gene ID:5971
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from A20, using Phospho-RELB-S573 Rabbit pAb (CABP1297) at 1:500 dilution.A20 cells were treated by PMA/TPA (200 nM) at 37℃ for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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