The RELB Polyclonal Antibody (CAB0519) is specifically designed for research involving RELB, a transcription factor known to play a crucial role in immune and inflammatory responses. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the RELB protein, this antibody enables scientists to detect and analyze RELB expression in a variety of cell types, making it ideal for studies in immunology and cancer research.RELB is a key regulator of immune and inflammatory pathways, making it an important target for studying diseases characterized by dysregulated immune responses, such as cancer and autoimmune disorders.
By understanding the role of RELB in immune function, researchers can gain valuable insights into potential therapeutic strategies for managing these conditions. The RELB Polyclonal Antibody is a valuable tool for researchers aiming to deepen their understanding of RELB's involvement in immune regulation and inflammatory processes.
Product Name:
RELB Rabbit Polyclonal Antibody
SKU:
CAB0519
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 296-436 of human RELB (NP_006500.2).
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in cytosol and nucleoplasm. Part of chromatin; nucleus; and transcription repressor complex. Colocalizes with centrosome. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma.
Purification Method:
Affinity purification
Gene ID:
5971
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RELB Rabbit pAb (CAB0519) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.