RARα Rabbit Polyclonal Antibody (CAB0370)
- SKU:
- CAB0370
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RARα Rabbit Polyclonal Antibody |
SKU: | CAB0370 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-457 of human RARα (NP_001019980.1). |
Sequence: | MYES VEVG GPTP NPFL VVDF YNQN RACL LPEK GLPA PGPY STPL RTPL WNGS NHSI ETQS SSSE EIVP SPPS PPPL PRIY KPCF VCQD KSSG YHYG VSAC EGCK GFFR RSIQ KNMV YTCH RDKN CIIN KVTR NRCQ YCRL QKCF EVGM SKES VRND RNKK KKEV PKPE CSES YTLT PEVG ELIE KVRK AHQE TFPA LCQL GKYT TNNS SEQR VSLD IDLW DKFS ELST KCII KTVE FAKQ LPGF TTLT IADQ ITLL KAAC LDIL ILRI CTRY TPEQ DTMT FSDG LTLN RTQM HNAG FGPL TDLV FAFA NQLL PLEM DDAE TGLL SAIC LICG DRQD LEQP DRVD MLQE PLLE ALKV YVRK RRPS RPHM FPKM LMKI TDLR SISA KGAE RVIT LKME IPGS MPPL IQEM LENS EGLD TLSG QPGG GGRD GGGL APPP GSCS PSLS PSSN RSSP ATHS P |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | RAR; NR1B1; RARalpha; RARα |
Positive Sample: | MCF7,K-562,Raji,THP-1,SH-SY5Y,Mouse testis,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 51kDa |
Observed MW: | 60kDa |
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
Purification Method: | Affinity purification |
Gene ID: | 5914 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |