Phospho-Rac1/Cdc42-S71 Rabbit Monoclonal Antibody (CABP1018)
- SKU:
- CABP1018
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
Description
Product Name: | Phospho-Rac1/Cdc42-S71 Rabbit Monoclonal Antibody |
SKU: | CABP1018 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around S71 of human Rac1/Cdc42CDC42 (P60953). |
Sequence: | PLSY P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CDC42Hs; G25K; TKS; Phospho-Rac1/Cdc42-S71 |
Positive Sample: | A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic ribonucleoprotein granule, Cytosol, dendritic spine, Extracellular exosome, Filopodium, Focal adhesion, Golgi transport complex, Leading edge membrane, Microtubule organizing center, Mitotic spindle, Phagocytic vesicle, Plasma membrane, Spindle midzone |
Calculated MW: | 24kDa |
Observed MW: | 24kDa |
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Purification Method: | Affinity purification |
Gene ID: | 998/5879 |
Clone Number: | ARC1563 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |