Phospho-POLR2A-S2 Rabbit Monoclonal Antibody (CABP0996)
- SKU:
- CABP0996
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Phospho-POLR2A-S2 Rabbit Monoclonal Antibody |
SKU: | CABP0996 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S2 of human POLR2A CTD repeat YSPTSPS. |
Tested Applications: | WB IHC-P IF/ICC ChIP ChIP-seq ELISA CUT&Tag |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 ChIP,5μg antibody for 10μg-15μg of ChromatinChIP-seq,1:50 - 1:100 CUT&Tag, 10⁵ cells /1 μg |
Synonyms: | RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; NEDHIB; RpIILS; hsRPB1; hRPB220; Phospho-POLR2A CTD-S2 |
Positive Sample: | MCF7, HeLa, C2C12, C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 217kDa |
Observed MW: | 270kDa |
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Purification Method: | Affinity purification |
Gene ID: | 5430 |
Clone Number: | ARC1540 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |