PLK1 Monoclonal Antibody (CAB21082)
- SKU:
- CAB21082
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | PLK1 Monoclonal Antibody |
SKU: | CAB21082 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Monkey |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 272-495 of human PLK1 (NP_005021.2). |
Sequence: | KHIN PVAA SLIQ KMLQ TDPT ARPT INEL LNDE FFTS GYIP ARLP ITCL TIPP RFSI APSS LDPS NRKP LTVL NKGL ENPL PERP REKE EPVV RETG EVVD CHLS DMLQ QLHS VNAS KPSE RGLV RQEE AEDP ACIP IFWV SKWV DYSD KYGL GYQL CDNS VGVL FNDS TRLI LYND GDSL QYIE RDGT ESYL TVSS HPNS LMKK ITLL KYFR NYMS EHLL KAGA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PLK; STPK13; PLK1 |
Positive Sample: | HeLa,Jurkat,K-562,COS-7,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Midbody, Nucleus, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle. |
Calculated MW: | 68kDa |
Observed MW: | 62kDa |
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
Purification Method: | Affinity purification |
Gene ID: | 5347 |
Clone Number: | ARC52311 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |