Phospho-PLC gamma 2 (PLCG2)-Y1217 Rabbit Polyclonal Antibody (CABP0805)
- SKU:
- CABP0805
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Phospho-PLC gamma 2 (PLCG2)-Y1217 Rabbit Polyclonal Antibody |
SKU: | CABP0805 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic phosphorylated peptide around Y1217 of human PLC gamma 2 (PLCG2) (NP_002652.2). |
Sequence: | FLYD T |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | FCAS3; APLAID; PLC-IV; PLC-gamma-2; Phospho-PLC gamma 2 (PLCG2)-Y1217 |
Positive Sample: | Raji |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome, perinuclear region of cytoplasm, plasma membrane, ruffle membrane |
Calculated MW: | 148kDa |
Observed MW: | 150kDa |
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Purification Method: | Affinity purification |
Gene ID: | 5336 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |