Phospho-PKCδ/θ-S643/676 Rabbit Polyclonal Antibody (CABP0567)
- SKU:
- CABP0567
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | Phospho-PKCδ/θ-S643/676 Rabbit Polyclonal Antibody |
SKU: | CABP0567 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic phosphorylated peptide around S643 of human PKCδ/θPRKCD (NP_001341605.1). |
Sequence: | RLSY S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PRKCD/PRKCQ; Phospho-PKCδ/θ-S643/676 |
Positive Sample: | RAW264.7 |
Conjugate: | Unconjugated |
Cellular Localization: | cell-cell junction, cytoplasm, cytosol, endolysosome, endoplasmic reticulum, extracellular exosome, extracellular region, mitochondrion, nuclear matrix, nucleoplasm, nucleus, perinuclear region of cytoplasm, plasma membrane |
Calculated MW: | 77kDa/80kDa/67kDa/74kDa/81kDa |
Observed MW: | 78kDa |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Purification Method: | Affinity purification |
Gene ID: | 5580/5588 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |