The Phospho-PKC mu (S910) Polyclonal Antibody is a valuable tool for researchers studying the protein kinase C mu (PKC mu) and its phosphorylation at serine 910. This antibody, raised in rabbits, has high specificity for human samples and is suitable for use in Western blot applications. By binding to the phosphorylated form of PKC mu, this antibody enables the detection and analysis of this critical signaling molecule in various cell types.PKC mu is a member of the protein kinase C family, known for its role in regulating various cellular processes, including cell growth, differentiation, and apoptosis. Phosphorylation of PKC mu at serine 910 has been linked to its activation and involvement in signaling pathways related to cell proliferation and survival.
Understanding the phosphorylation status of PKC mu can provide valuable insights into its function and its potential role in diseases such as cancer.The Phospho-PKC mu (S910) Polyclonal Antibody is a valuable tool for researchers interested in studying the role of PKC mu in cellular signaling and disease. Its high specificity and sensitivity make it an ideal choice for studies in molecular biology, cell biology, and oncology. By enabling the detection of phosphorylated PKC mu, this antibody opens up new opportunities for exploring the functions and therapeutic targeting of this important protein kinase.
Product Name:
Phospho-PKC mu-S910 Polyclonal Antibody
SKU:
CABP1380
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic phosphorylated peptide around S910 of human PKC mu (NP_002733.2).
The protein encoded by this gene is a serine/threonine protein kinase involved in many cellular processes, including Golgi body membrane integrity and transport, cell migration and differentiation, MAPK8/JNK1 and Ras pathway signaling, MAPK1/3 (ERK1/2) pathway signaling, cell survival, and regulation of cell shape and adhesion.
Purification Method:
Affinity purification
Gene ID:
5587
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from 293F cells using Phospho-PKC mu-S910 Rabbit pAb (CABP1380) at 1:4000 dilution. 293F cells were treated by PMA/TPA (200 nM) at 37℃ for 15 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.