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Phospho-PIK3R1/PIK3R2/PIK3R3-Y467 Polyclonal Antibody (CABP0427)

SKU:
CABP0427
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
$563
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Description

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Product Name:Phospho-PIK3R1/PIK3R2/PIK3R3-Y467 Polyclonal Antibody
SKU:CABP0427
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A phospho specific peptide corresponding to residues surrounding Y467 of human PIK3R1/2/3
Tested Applications:WB
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:PIK3R1/PIK3R2/PIK3R3; Phospho-PI3KP85α/P55γ/P85β-Y467/Y464/Y199
Positive Sample:293
Conjugate:Unconjugated
Cellular Localization:cell-cell junction, cis-Golgi network, cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm, plasma membrane
Calculated MW:42-54kDa/81-84kDa
Observed MW:85kDa

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

Purification Method:Affinity purification
Gene ID:5295/5296/8503
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from 293 cells, using Phospho-PI3KP85α/P55γ/P85β-Y467/Y464/Y199 Rabbit pAb (CABP0427).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.

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