Phospho-PIK3R1/PIK3R2/PIK3R3-Y467 Polyclonal Antibody (CABP0427)
- SKU:
- CABP0427
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | Phospho-PIK3R1/PIK3R2/PIK3R3-Y467 Polyclonal Antibody |
SKU: | CABP0427 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A phospho specific peptide corresponding to residues surrounding Y467 of human PIK3R1/2/3 |
Tested Applications: | WB |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PIK3R1/PIK3R2/PIK3R3; Phospho-PI3KP85α/P55γ/P85β-Y467/Y464/Y199 |
Positive Sample: | 293 |
Conjugate: | Unconjugated |
Cellular Localization: | cell-cell junction, cis-Golgi network, cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm, plasma membrane |
Calculated MW: | 42-54kDa/81-84kDa |
Observed MW: | 85kDa |
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Purification Method: | Affinity purification |
Gene ID: | 5295/5296/8503 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |