Phospho-PERK-T982 Monoclonal Antibody (CABP1420)
- SKU:
- CABP1420
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
Frequently bought together:
Description
Product Name: | Phospho-PERK-T982 Monoclonal Antibody |
SKU: | CABP1420 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around T982 of human PERK. |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | PEK; WRS; PERK; Phospho-PERK-T982 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane. |
Calculated MW: | 125kDa |
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Purification Method: | Affinity purification |
Gene ID: | 9451 |
Clone Number: | ARC58933 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |