The PDLIM5 Polyclonal Antibody (CAB10006) is a valuable tool for researchers studying PDLIM5, a protein involved in various cellular functions. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.PDLIM5, also known as Enigma homolog protein, is a cytoskeletal protein that plays a role in cell adhesion, migration, and signaling. Its involvement in these processes makes it a key protein of interest in studies focusing on cell biology, cancer research, and developmental biology.
By targeting the PDLIM5 protein, researchers can analyze its expression levels and localization within different cell types, aiding in the understanding of its function and potential implications in disease states. The PDLIM5 Polyclonal Antibody provides a reliable tool for investigating the role of PDLIM5 in various cellular processes, making it an essential resource for researchers in these fields.
Product Name:
PDLIM5 Polyclonal Antibody
SKU:
CAB22013
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PDLIM5 (NP_006448.5).
actin cytoskeleton, cell projection, cytosol, postsynaptic density, presynapse, Z disc
Calculated MW:
64kDa
Observed MW:
64kDa
This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10611
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of HeLa, using PDLIM5 Rabbit pAb (CAB22013) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.