Phospho-PDGFRA-Y1018 Rabbit Polyclonal Antibody (CABP0615)
- SKU:
- CABP0615
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
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Description
Product Name: | Phospho-PDGFRA-Y1018 Rabbit Polyclonal Antibody |
SKU: | CABP0615 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around Y1018 of human PDGFRA (NP_006197.1). |
Sequence: | SGYI I |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CD140A; PDGFR2; PDGFR-2; Phospho-PDGFR alpha-Y1018 |
Positive Sample: | HepG2+UV,HepG2+EGF |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 123kDa |
Observed MW: | 200kDa |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Purification Method: | Affinity purification |
Gene ID: | 5156 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |