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[KO Validated] SPK Rabbit Polyclonal Antibody (CAB19947)

SKU:
CAB19947
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

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Product Name:[KO Validated] SPK Rabbit Polyclonal Antibody
SKU:CAB19947
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-322 of human SPK (NP_060962.2).
Sequence:MEGI SNFK TPSK LSEK KKSV LCST PTIN IPAS PFMQ KLGF GTGV NVYL MKRS PRGL SHSP WAVK KINP ICND HYRS VYQK RLMD EAKI LKSL HHPN IVGY RAFT EAND GSLC LAME YGGE KSLN DLIE ERYK ASQD PFPA AIIL KVAL NMAR GLKY LHQE KKLL HGDI KSSN VVIK GDFE TIKI CDVG VSLP LDEN MTVT DPEA CYIG TEPW KPKE AVEE NGVI TDKA DIFA FGLT LWEM MTLS IPHI NLSN DDDD EDKT FDES DFDD EAYY AALG TRPP INME ELDE SYQK VIEL FSVC TNED PKDR PSAA HIVE ALET DV
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:SPK; CT84; TOPK; HEL164; Nori-3; PK
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:nucleus
Calculated MW:36kDa
Observed MW:36kDa

This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:55872
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and SPK knockout (KO) 293T cells, using [KO Validated] SPK Rabbit pAb (CAB19947) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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