The Phospho-p90RSK/RSK1/RPS6KA1 (T348) Polyclonal Antibody is a valuable tool for researchers studying the phosphorylation of the p90 ribosomal S6 kinase (p90RSK), also known as RSK1 or RPS6KA1. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it suitable for Western blot applications.Phosphorylation of p90RSK at threonine 348 plays a crucial role in the activation of this kinase, which is involved in various cellular processes including cell proliferation, survival, and differentiation. By targeting this specific phosphorylation site, researchers can study the activation status of p90RSK and its downstream signaling pathways in different cell types and experimental conditions.
The Phospho-p90RSK/RSK1/RPS6KA1 (T348) Polyclonal Antibody is an essential tool for investigating the regulatory mechanisms of p90RSK and its potential role in diseases such as cancer, neurodegenerative disorders, and metabolic conditions. Its high specificity and sensitivity make it a reliable choice for immunology and cancer research studies where the phosphorylation status of p90RSK is of interest.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
6195
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of HeLa, using Phospho-p90Rsk/RSK1/RPS6KA1-T348 antibody (CABP1397) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
