Phospho-p70 S6 Kinase 1-T421/S424 Rabbit Monoclonal Antibody (CABP0502)
- SKU:
- CABP0502
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Phospho-p70 S6 Kinase 1-T421/S424 Rabbit Monoclonal Antibody |
SKU: | CABP0502 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthesized peptide derived from human Phospho-S6K1 (T421 + S424).(NP_001258989.1) |
Sequence: | RRFI GSPR TPVS PVKF SPGD |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha; Phospho-p70 S6 Kinase 1-T421/S424 |
Positive Sample: | NIH/3T3+serum,C6+serum |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, Mitochondrion outer membrane, Mitochondrion, Nucleus, synapse, synaptosome. |
Calculated MW: | 59kDa |
Observed MW: | 65kDa |
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Purification Method: | Affinity purification |
Gene ID: | 6198 |
Clone Number: | ARC0107 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |