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Anti-Phospho-p53-S37 Antibody (CABP1110)

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SKU:
CABP1110
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
€159 - €419

Description

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Anti-Phospho-p53-S37 Antibody (CABP1110)

The Phospho-p53 (S37) Rabbit Polyclonal Antibody (CABP1110) is designed for research involving the phosphorylation of the p53 protein at serine 37, a key post-translational modification that regulates its activity in cellular processes such as DNA repair and apoptosis. This antibody, raised in rabbits, is highly specific for the phosphorylated form of p53 and is validated for use in Western blot applications. It allows for the detection and analysis of phospho-p53 (S37) in various cell types, making it ideal for studies in cancer research and understanding the role of p53 in tumor suppression mechanisms.

Phospho-p53 (S37) is a critical regulator of p53 function, influencing its stability and activity in response to cellular stress and DNA damage. Dysregulation of p53 phosphorylation at serine 37 has been implicated in various human cancers, making it a promising therapeutic target for cancer treatment and drug development. By studying the phosphorylation status of p53 at serine 37, researchers can gain insights into the molecular mechanisms underlying tumorigenesis and identify new strategies for cancer therapy.

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