Phospho-NPM1-T199 Rabbit Polyclonal Antibody (CABP0836)
- SKU:
- CABP0836
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Phospho-NPM1-T199 Rabbit Polyclonal Antibody |
SKU: | CABP0836 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around T199 of human NPM1 (NP_001032827.1). |
Sequence: | RDTP A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | B23; NPM; Phospho-NPM1-T199 |
Positive Sample: | HeLa+Nocodazole |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, nucleolus, nucleoplasm. |
Calculated MW: | 33kDa |
Observed MW: | 38kDa |
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified.
Purification Method: | Affinity purification |
Gene ID: | 4869 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |