The eNOS Polyclonal Antibody (CAB15075) is a valuable tool for research involving endothelial nitric oxide synthase (eNOS), a key enzyme involved in the production of nitric oxide and regulation of vascular tone. This antibody, raised in rabbits, is highly specific and reacts strongly with human, mouse, and rat samples, making it suitable for a wide range of experimental applications.eNOS is crucial for cardiovascular health, playing a vital role in regulating blood pressure and vascular function. Dysregulation of eNOS has been implicated in various cardiovascular diseases, making it a promising target for drug development.
The eNOS Polyclonal Antibody facilitates the detection and analysis of eNOS expression in various tissues and cell types, providing insights into its role in health and disease.With its high specificity and sensitivity, the eNOS Polyclonal Antibody is an essential tool for researchers studying vascular biology, cardiovascular diseases, and nitric oxide signaling pathways. Its versatility and reliability make it a valuable asset for advancing our understanding of eNOS function and developing new therapeutic strategies for cardiovascular disorders.
Product Name:
eNOS Rabbit Polyclonal Antibody
SKU:
CAB15075
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 639-738 of human eNOS (NP_000594.2).
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4846
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using eNOS Rabbit pAb (CAB15075) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.