Phospho-IκBα-Y42 Rabbit Polyclonal Antibody (CABP0420)
- SKU:
- CABP0420
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Phospho-IκBα-Y42 Rabbit Polyclonal Antibody |
SKU: | CABP0420 |
Size: | 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A phospho specific peptide corresponding to residues surrounding Y42 of human IκBα |
Tested Applications: | WB |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IKBA; MAD-3; NFKBI; EDAID2; Phospho-IκBα-Y42 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 36kDa |
Observed MW: | 40kDa |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Purification Method: | Affinity purification |
Gene ID: | 4792 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |