Phospho-NF-κB2-S870 Rabbit Polyclonal Antibody (CABP0419)
- SKU:
- CABP0419
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
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Description
Product Name: | Phospho-NF-κB2-S870 Rabbit Polyclonal Antibody |
SKU: | CABP0419 |
Size: | 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S870 of human NF-κB2 |
Tested Applications: | WB |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100; Phospho-NF-κB2-S870 |
Positive Sample: | MDA-MB-435 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 97kDa |
Observed MW: | 120kDa |
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4791 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |