NFATC4 Rabbit Polyclonal Antibody (CAB17511)
- SKU:
- CAB17511
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NFATC4 Rabbit Polyclonal Antibody |
SKU: | CAB17511 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 560-710 of human NFATC4 (NP_004545.2). |
Sequence: | QGGG KVVS VQAA SVPI ECSQ RSAQ ELPQ VEAY SPSA CSVR GGEE LVLT GSNF LPDS KVVF IERG PDGK LQWE EEAT VNRL QSNE VTLT LTVP EYSN KRVS RPVQ VYFY VSNG RRKR SPTQ SFRF LPVI CKEE PLPD SSLR GFPS ASAT PFG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NFAT3; NF-AT3; NF-ATC4; NFATC4 |
Positive Sample: | SKOV3,HepG2,A-549,Mouse lung,Mouse kidney,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, nuclear speck, nucleus |
Calculated MW: | 95kDa |
Observed MW: | 108kDa |
This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4776 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |