The Phospho-NDRG1 (S330) Polyclonal Antibody (CABP0807) is a valuable tool for researchers studying the phosphorylation of NDRG1 at serine 330. NDRG1 is a protein involved in various cellular processes, including cell growth, differentiation, and stress response. The antibody, produced in rabbits, is highly specific to the phosphorylated form of NDRG1 at serine 330, making it ideal for use in Western blot applications.Phosphorylation at serine 330 has been linked to the regulation of NDRG1 activity and its involvement in signaling pathways related to cell proliferation and survival. By targeting this specific phosphorylation site, researchers can gain insights into the molecular mechanisms underlying these cellular processes.
The antibody's high reactivity with human samples further enhances its utility in the study of diseases such as cancer, where dysregulation of NDRG1 phosphorylation has been implicated.Overall, the Phospho-NDRG1 (S330) Polyclonal Antibody (CABP0807) is a valuable tool for investigating the role of NDRG1 phosphorylation in cellular signaling pathways and disease pathology. Its specificity and reliability make it a valuable asset for researchers in the fields of molecular biology, oncology, and cell signaling.
Product Name:
Phospho-NDRG1-S330 Rabbit Polyclonal Antibody
SKU:
CABP0807
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic phosphorylated peptide around S330 of human NDRG1 (NP_001128714.1).
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10397
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using Phospho-NDRG1-S330 Rabbit pAb (CAB2142).Jurkat cells were treated by Calyculin A (100nM) for 30 minutes.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
