The Phospho-MSN/RDX/EZR (T558) Rabbit Polyclonal Antibody (PACO04362) is a valuable tool for researchers studying protein phosphorylation and its role in cell signaling pathways. This antibody is highly specific for detecting phosphorylated forms of the Moesin (MSN), Radixin (RDX), and Ezrin (EZR) proteins at threonine 558 in human samples. Phosphorylation of MSN, RDX, and EZR at threonine 558 is known to play a critical role in cytoskeletal organization, cell motility, and cell membrane dynamics. This antibody allows for the detection and analysis of phosphorylated MSN, RDX, and EZR in various cell types, making it ideal for studies focused on cell biology, cancer research, and signal transduction pathways.
By understanding the phosphorylation status of MSN, RDX, and EZR at threonine 558, researchers can gain insights into the complex regulatory mechanisms that control cell behavior and function. This antibody is validated for use in Western blot applications and provides a reliable tool for investigating the functional significance of phosphorylated MSN, RDX, and EZR in both normal and disease states.
Antibody Name:
Phospho-MSN/RDX/EZR (T558) Antibody
Antibody SKU:
PACO04362
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from human Moesin/Ezrin/Radixin around the phosphorylation site of T558.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
NCBI Summary:
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
